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Variable Response to Naltrexone in Patients With Hailey-Hailey Disease
JAMA Dermatol
March 2018
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885838/
Hailey-Hailey disease (HHD) is a genetic intraepidermal blistering disorder characterized by chronic macerated erosions in intertriginous areas. The recent report of 2 case series demonstrating the efficacy of low-dose naltrexone in the treatment of HHD represents exciting progress in the management of a disease with limited therapeutic options. Herein we present 3 additional cases of HHD demonstrating varying responses to naltrexone.
Keywords: naltrexone, hailey-hailey disease, case studies, HHD, LDN
Keywords by Erin Williams, student, St. Louis College of Pharmacy