What is the benefit of dosing of Low Dose Naltrexone (LDN) at night?

What is the benefit of dosing of Low Dose Naltrexone (LDN) at night?

What's the special benefit of night metabolism? Ooh. Okay, so this goes back to endorphins and immune system function and good sleeps, and this sort of idea, like, good sleep, good rest, good recovery. And so this seemed to be fall in line.  Why nighttime? We know that your immune system is more active at night, and so we might be able to find that it works better for some patients at night. 

But cardiology, very cool. There's a whole bunch of new studies that talk about cardiovascular function, so decrease in inflammation, but also increase cardiac output in an appropriate good way and prevents some negative response to high stress loading. There are some new papers that were done in some mice, but we're starting to see cardiologists using it for the twofer effect. So improved cardiac function as well as decrease in inflammation.

So if your cardiologist said, take LDN in the morning, I'm going to line up with this cardiologist, you're like, yes, stick with air. They're doing it for a twofer effect. They want to see good cardiovascular function as well as the immunomodultary anti inflammatory function. So for you, there may not be an improved benefit. The half-life is going to be onset in the first half hour and over the next for the rest of the day, so stick with it during the day. I hope that helps. And if your cardiologist says, yeah, you can take it at night, just see how your heart feels and how you feel. And if you're finding like, oh, yeah, it works better for me in the day or works better for me in the night, that's for you. But I think, think your cardiologists, they're on the right path with daytime dosing. And anyone who gets negative dreams or very intense dreams or that 3:00 endorphin rush where they wake up and they're like, whoo, I'm awake. It's 3:00 in the morning. What do I do? I go and I have a bowl of cereal because I think I'm hungry, but it might be that my Naltrexerone is kicking in. Maybe switch it to the morning so you don't have that nighttime wake-up.