Due to its pain-relieving and anti-inflammatory activities, LDN can help with many different types of arthritis. In my personal experience, it seems to make more of an impact on inflammatory arthritis. This would include any of the autoimmune types including rheumatoid arthritis and Lupus. Now in terms of osteoarthritis, you have more of a mechanical problem with narrowing of the joint and loss of cartilage, not necessarily always with inflammation. In those patients, I haven’t seen LDN make as much of an impact. But again everyone is different so there’s no reason not to try it if a patient is interested.