What is the Suggested Dosing of Low Dose Naltrexone (LDN) for Knee Pain?

LDN Specialist Pharmacist Michelle Moser
Pharmacist Michelle Moser

What is the Suggested Dosing of Low Dose Naltrexone (LDN) for Knee Pain?

I've been taking LDN for about four years for my knee pain with great results however, now I am experiencing more bone on bone pain. I'm up to 4.5 milligrams. Would it benefit me to go down to a lower dose?

There is not a direct answer. You can try it. Try taking two milligrams at one part of the day or 2.25 milligrams at one point of the day and two and a half or 2.25 the other end of the day. If it's helpful and you want to play around with the dose talk to your provider, talk to your compounding pharmacist.

I talked about Dr Norman earlier and what he does, especially with these kinds of situations, is there's ways to actually build the synovial tissue or to try to keep the bone off bone. There's a way to help rebuild that gap. He starts with teeny doses; 0.1 milligram once a day, twice a day, three times a day, four times a day, and then slowly increases from there. And he has tremendous results at his pain clinic. 

What I'm saying is try it and if it doesn't help then go back to what you were in dosage. A lot of times less is more with LDN. It's okay to take less than 4.5 milligram you probably are going to see good results even at a lower dose.